David A Bennett Selected Research

DNA (Deoxyribonucleic Acid)

1/2023	Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.
1/2023	Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.
1/2022	Circulating Cell-Free Genomic DNA Is Associated with an Increased Risk of Dementia and with Change in Cognitive and Physical Function.
10/2021	A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
10/2020	Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy.
6/2017	A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
9/2016	Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model.
9/2014	Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.

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David A Bennett Research Topics

Disease

294	Alzheimer Disease (Alzheimer's Disease) 06/2024 - 02/2002
176	Cognitive Dysfunction 04/2024 - 02/2002
126	Dementia (Dementias) 05/2024 - 02/2002
31	Amyloid Plaque 03/2024 - 05/2004
27	Hippocampal Sclerosis 02/2024 - 11/2013
23	Infarction (Infarctions) 04/2024 - 01/2012
20	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2024 - 08/2005
18	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 04/2024 - 07/2012
18	Atherosclerosis 04/2024 - 01/2017
15	Arteriolosclerosis 04/2024 - 08/2017
14	Inflammation (Inflammations) 04/2024 - 01/2013
13	Cerebral Infarction 01/2023 - 01/2006
10	Brain Diseases (Brain Disorder) 03/2024 - 10/2020
10	Parkinson Disease (Parkinson's Disease) 01/2024 - 03/2005
10	Neuroinflammatory Diseases 01/2024 - 04/2016
9	Disease Progression 04/2024 - 10/2007
9	Parkinsonian Disorders (Parkinsonism) 01/2023 - 11/2005
8	limbic-predominant age-related TDP-43 encephalopathy 03/2024 - 10/2020
7	Vascular Diseases (Vascular Disease) 04/2024 - 02/2007
7	Proteostasis Deficiencies 03/2024 - 11/2016
7	Atrophy 01/2022 - 05/2014
7	Stroke (Strokes) 04/2021 - 03/2005
7	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2021 - 01/2011
6	Brain Infarction 02/2024 - 01/2013
6	Intracranial Arteriosclerosis (Cerebral Atherosclerosis) 01/2023 - 01/2020
6	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 12/2022 - 03/2010
5	Genetic Risk Score 03/2024 - 04/2015
5	Neuroblastoma 11/2023 - 01/2013
5	Amyloidosis 01/2023 - 01/2018
5	Frailty 01/2022 - 08/2008
5	Memory Disorders (Memory Loss) 01/2019 - 04/2005
4	Insulin Resistance 02/2024 - 04/2012
4	Pain (Aches) 01/2023 - 09/2010
4	Pathologic Processes 01/2022 - 01/2017
4	Amyloid angiopathy 01/2021 - 11/2015
4	Chronic Disease (Chronic Diseases) 01/2020 - 08/2008
4	Synucleinopathies 01/2018 - 08/2005
4	Lewy Body Disease (Lewy Body Dementia) 01/2017 - 04/2014
3	Tauopathies 01/2024 - 12/2015
3	Neurobehavioral Manifestations 01/2023 - 06/2013
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2022 - 01/2020
3	TDP-43 Proteinopathies 01/2021 - 01/2018

Drug/Important Bio-Agent (IBA)

89	Amyloid (Amyloid Fibrils)IBA 05/2024 - 03/2004
84	Apolipoproteins E (ApoE)IBA 03/2024 - 05/2004
71	Proteins (Proteins, Gene)FDA Link 04/2024 - 08/2003
48	Biomarkers (Surrogate Marker)IBA 06/2024 - 10/2005
38	DNA-Binding Proteins (DNA Binding Protein)IBA 04/2024 - 03/2010
36	ApolipoproteinsIBA 01/2024 - 02/2003
25	Amyloid beta-PeptidesIBA 04/2024 - 01/2007
21	RNA (Ribonucleic Acid)IBA 01/2024 - 01/2016
15	Messenger RNA (mRNA)IBA 04/2024 - 09/2004
13	CholesterolIBA 01/2023 - 01/2005
11	Peptides (Polypeptides)IBA 02/2024 - 12/2011
10	Cholinergic Agents (Cholinergics)IBA 11/2023 - 02/2002
10	Apolipoprotein E4IBA 11/2022 - 05/2008
9	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2015
8	Indicators and Reagents (Reagents)IBA 04/2024 - 01/2006
8	LipidsIBA 03/2023 - 08/2009
8	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 09/2014
7	SynucleinsIBA 03/2024 - 07/2012
7	Insulin (Novolin)FDA Link 02/2024 - 01/2018
7	Protein Isoforms (Isoforms)IBA 12/2023 - 02/2008
7	EnzymesIBA 11/2023 - 02/2003
7	SilverIBA 06/2022 - 05/2006
6	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 01/2018
6	ProteomeIBA 10/2023 - 01/2021
5	Hemoglobins (Hemoglobin)IBA 02/2024 - 01/2012
5	Nerve Growth Factor (NGF)IBA 01/2023 - 08/2003
5	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 04/2005
4	UbiquitinIBA 03/2024 - 01/2004
4	Mitochondrial DNA (mtDNA)IBA 05/2023 - 11/2021
4	ChromatinIBA 01/2023 - 01/2014
4	Antihypertensive Agents (Antihypertensives)IBA 01/2023 - 01/2006
4	Histones (Histone)IBA 01/2023 - 01/2018
4	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 10/2022 - 07/2003
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2022 - 05/2014
4	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 01/2022 - 02/2002
4	CalciumIBA 01/2022 - 01/2021
4	AntibodiesIBA 01/2019 - 08/2011
4	Caspase 6IBA 12/2016 - 09/2004
4	Antipsychotic Agents (Antipsychotics)IBA 08/2008 - 11/2005
3	Estrogens (Estrogen)FDA Link 02/2024 - 02/2008
3	Amyloidogenic ProteinsIBA 01/2024 - 01/2017
3	Transfer RNA (tRNA)IBA 11/2023 - 02/2023
3	Estrogen ReceptorsIBA 10/2023 - 02/2008
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 01/2012
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 01/2020
3	Eicosapentaenoic AcidIBA 10/2022 - 07/2003
3	tau Proteins (tau Protein)IBA 01/2022 - 01/2015
3	Phospholipases A2 (Phospholipase A2)IBA 01/2022 - 01/2021
3	AntioxidantsIBA 01/2022 - 06/2002
3	complexin IIIBA 05/2021 - 01/2017
3	complexin IIBA 05/2021 - 01/2017
3	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 01/2019
3	C-Reactive ProteinIBA 01/2019 - 01/2013

Therapy/Procedure

14	Activities of Daily Living (ADL) 05/2024 - 10/2006
12	Therapeutics 01/2023 - 02/2002
6	Dietary Approaches To Stop Hypertension 06/2023 - 09/2015
4	Precision Medicine 06/2023 - 01/2018
4	Mediterranean Diet 06/2023 - 10/2014